Proper Use
Drug information provided by: Merative, Micromedex®
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
This medicine comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Swallow the delayed-release tablet whole. Do not split, crush, or chew it. You may take the tablet with or without food.
For delayed-release oral suspension granules:
- Applesauce method:
- 1. Open packet.
- 2. Mix the packet contents with 1 teaspoonful of applesauce. Do not mix with water, other liquids, or food.
- 3. Swallow the mixture at least 30 minutes before a meal. Take it within 10 minutes after you mix it.
- 4. Sip some water after you swallow the mixture. This will make sure all of the granules get all the way to your stomach.
- 5. Do not chew or crush the granules. Do not divide the packet contents to make smaller doses.
- Apple juice method:
- 1. Open packet.
- 2. Mix the packet contents with 1 teaspoon of apple juice in a small cup or container.
- 3. Stir for 5 seconds (granules will not dissolve) and swallow it immediately or take it at least 30 minutes before a meal.
- 4. Rinse the container with apple juice to make sure you get all of the medicine. Swallow it immediately.
- 5. Do not chew or crush the granules. Do not divide the packet contents to make smaller doses.
- Feeding tube:
- 1. Pour the packet contents in a 2-ounce (60 mL) catheter-tip syringe.
- 2. Clear any clogs from the feeding tube before you put this medicine mixture into the tube.
- 3. Add 10 mL of apple juice into the syringe. Gently tap or shake the barrel of the syringe to help rinse the syringe and tube.
- 4. Repeat with an additional 10 mL of apple juice. No granules should remain in the syringe.
- 5. Take this medicine at least 30 minutes before a meal.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage forms (delayed-release tablets or suspension):
- For erosive esophagitis:
- Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions.
- Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.
- Children 5 years of age and older weighing 15 to 39 kg—20 mg once a day for up to 8 weeks.
- Children younger than 5 years of age—Use and dose must be determined by your doctor.
- For Zollinger-Ellison syndrome:
- Adults—At first, 40 milligrams (mg) 2 times a day. Your doctor may increase your dose as needed.
- Children—Use and dose must be determined by your doctor.
Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
From Mayo Clinic to your inbox
Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview.
To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.
Portions of this document last updated: July 01, 2024
Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
.
FAQs
It's usual to take it once a day in the morning. If you take pantoprazole 2 times a day, take 1 dose in the morning and 1 dose in the evening. It's best to take it 1 hour before a meal. Swallow tablets whole with water or juice.
What is the correct way to take pantoprazole? ›
It's usual to take it once a day in the morning. If you take pantoprazole 2 times a day, take 1 dose in the morning and 1 dose in the evening. It's best to take it 1 hour before a meal. Swallow tablets whole with water or juice.
What is the route of administration for pantoprazole? ›
Administer pantoprazole sodium for injection intravenously through a dedicated line or through a Y-site. Flush the intravenous line before and after administration of pantoprazole sodium for injection with either 5% Dextrose Injection, USP, 0.9% Sodium Chloride Injection, USP, or Lactated Ringer's Injection, USP.
Is it better to take pantoprazole on an empty stomach? ›
You can eat and drink normally while taking pantoprazole, but it's best to take it an hour before a meal. It's best to avoid foods that seem to make your symptoms worse, such as rich, spicy and fatty foods. It also helps to cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.
What are the special considerations for pantoprazole? ›
Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more. Call your doctor right away if you have severe bone pain or are unable to walk or sit normally.
How to take PPI correctly? ›
The medications, available both over the counter and by prescription, are most effective when taken on an empty stomach. PPIs circulate in the blood to block the stomach's acid pumps, which are activated when you eat.
How many minutes before eating should I take pantoprazole? ›
For the treatment of conditions where the stomach produces too much acid, pantoprazole is usually taken twice a day. The delayed-release tablets are usually taken with or without food, and the granules are usually taken 30 minutes before a meal. Take pantoprazole at around the same time(s) every day.
What is the protocol for pantoprazole? ›
Adults—40 milligrams (mg) once a day for up to 8 weeks. Your doctor may want you to take pantoprazole for more than 8 weeks for certain conditions. Children 5 years of age and older weighing 40 kilograms (kg) or more—40 mg once a day for up to 8 weeks.
Is pantoprazole given IV or IM? ›
How should this medicine be used? Pantoprazole injection comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. For the treatment of GERD, pantoprazole injection is usually given once a day for 7 to 10 days.
What is the route of administration for PPI? ›
PPIs are taken by mouth. They are available as tablets or capsules. Commonly, these medicines are taken 30 minutes before the first meal of the day.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription (eg, atazanavir, nelfinavir, Reyataz®, Viracept®) or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
What foods should you avoid while taking pantoprazole? ›
Pantoprazole is a proton pump inhibitor that can be used to treat gastrointestinal reflux disease (GERD) and stomach ulcers. Foods that trigger GERD and worsen heartburn symptoms can lessen the effects of pantoprazole. Try to avoid fried, greasy foods, and spicy foods when taking pantoprazole.
Which is safer, pantoprazole or omeprazole? ›
Generally, both omeprazole and pantoprazole provide safe options to help manage acid reflux and other stomach acid-related conditions. In rare cases, individuals may develop more severe side effects with omeprazole or pantoprazole.
What should be monitored when taking pantoprazole? ›
Patients who are prescribed pantoprazole require monitoring for signs and symptoms of gastroesophageal reflux disease and peptic ulcer disease. If symptoms of these conditions arise, an increase in dosage or medication change should merit clinician consideration.
What organ does pantoprazole affect? ›
Pantoprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
What is a serious side effect of pantoprazole? ›
Severe Skin Reactions.
Pantoprazole can cause severe skin reactions, such as Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN), that can lead to death if not treated. If you develop a rash, stop pantoprazole and call your healthcare provider right away.
What medications cannot be taken with pantoprazole? ›
Pantoprazole can interact with warfarin, HIV drugs, iron supplements, and more. Many of pantoprazole's interactions are related to its ability to lower acid in your stomach. Several medications need stomach acid to be absorbed. Compared to other PPIs, pantoprazole tends to have fewer interactions.